Levemir flexpen 100u/ml stylo 3ml5
Levemir flexpen 100u/ml is a sterile solution of insulin detemir for use as an injection. Insulin detemir is a long-acting basal insulin analog, with up to 24 hours duration of action, produced by a process that includes expression of recombinant DNA in Saccharomyces cerevisiae followed by chemical modification.
Levemir 10 mL vial, 100 Units/mL
Levemir FlexPen 3mL, 100 Units/mL ad FlexTouch 3mL, 100 Units/mL
Acts via specific membrane-bound receptors on target tissues to regulate metabolism of carbohydrate, protein, and fats. Target organs include the liver, skeletal muscle, and adipose tissue.
Onset of action: 3-4 hours, Cmax 6-8 hours post-dose
Systemic bioavailability: 60%
Distribution: Vd: 0.1 L/kg
Protein binding: >98% (albumin)
Half-life elimination: 5-7 hours (dose dependent)
Initiation, Type I Diabetes Approximately 1/3 of the total daily insulin requirement administered in 1-2 divided doses, a rapid or short acting pre-meal insulin should be used to complete the balance of the total daily insulin requirement.